Detalhe da pesquisa
1.
Dyrk1a gene dosage in glutamatergic neurons has key effects in cognitive deficits observed in mouse models of MRD7 and Down syndrome.
PLoS Genet
; 17(9): e1009777, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34587162
2.
Reliable and robust droplet digital PCR (ddPCR) and RT-ddPCR protocols for mouse studies.
Methods
; 191: 95-106, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32721466
3.
Droplet digital PCR or quantitative PCR for in-depth genomic and functional validation of genetically altered rodents.
Methods
; 191: 107-119, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33838271
4.
Variability in Genome Editing Outcomes: Challenges for Research Reproducibility and Clinical Safety.
Mol Ther
; 28(6): 1422-1431, 2020 06 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32243835
5.
A new mouse model of ARX dup24 recapitulates the patients' behavioral and fine motor alterations.
Hum Mol Genet
; 27(12): 2138-2153, 2018 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29659809
6.
Distinct fibroblast lineages determine dermal architecture in skin development and repair.
Nature
; 504(7479): 277-281, 2013 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-24336287
7.
E4F1-mediated control of pyruvate dehydrogenase activity is essential for skin homeostasis.
Proc Natl Acad Sci U S A
; 113(39): 11004-9, 2016 09 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-27621431
8.
How much do we know about the function of mammalian genes?
BMC Biol
; 21(1): 301, 2023 12 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38155353
9.
Ketohexokinase knockout mice, a model for essential fructosuria, exhibit altered fructose metabolism and are protected from diet-induced metabolic defects.
Am J Physiol Endocrinol Metab
; 315(3): E386-E393, 2018 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29870677
10.
Physiological Expression of AMPKγ2RG Mutation Causes Wolff-Parkinson-White Syndrome and Induces Kidney Injury in Mice.
J Biol Chem
; 291(45): 23428-23439, 2016 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27621313
11.
Modeling human disease in rodents by CRISPR/Cas9 genome editing.
Mamm Genome
; 28(7-8): 291-301, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28677007
12.
Aneuploidy screening of embryonic stem cell clones by metaphase karyotyping and droplet digital polymerase chain reaction.
BMC Cell Biol
; 17(1): 30, 2016 08 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27496052
13.
Introduction to mammalian genome special issue: the microbiome in human health and disease.
Mamm Genome
; 32(4): 205, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34195895
14.
Absence of TI-VAMP/Vamp7 leads to increased anxiety in mice.
J Neurosci
; 32(6): 1962-8, 2012 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-22323709
15.
CRISMERE Chromosome Engineering in Mouse and Rat.
Methods Mol Biol
; 2631: 277-297, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36995673
16.
Increased On-Target Rate and Risk of Concatemerization after CRISPR-Enhanced Targeting in ES Cells.
Genes (Basel)
; 14(2)2023 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36833328
17.
Development of HPV16 mouse and dog models for more accurate prediction of human vaccine efficacy.
Lab Anim Res
; 39(1): 14, 2023 Jun 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37308929
18.
Highly-efficient, fluorescent, locus directed cre and FlpO deleter mice on a pure C57BL/6N genetic background.
Genesis
; 50(6): 482-9, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22121025
19.
Mouse large-scale phenotyping initiatives: overview of the European Mouse Disease Clinic (EUMODIC) and of the Wellcome Trust Sanger Institute Mouse Genetics Project.
Mamm Genome
; 23(9-10): 600-10, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22961258
20.
The mammalian gene function resource: the International Knockout Mouse Consortium.
Mamm Genome
; 23(9-10): 580-6, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22968824